Aim and purpose:
Plants are considered as a worthy source of effective antimicrobial drugs. Therefore can serve as a pre-requisite for the discovery of new active components. Bidens biternata, Caralluma tuberculate, Cedrela serrata, Myrsine africana, Berginia ciliate, Paeonia emodi and Aconitum heterophyllum are important ethnomedicinal plants of Pakistan. The present study is aimed to evaluate the antibacterial and antifungal activities of extracts obtained from these plant.

Method: Methanol and chloroform extracts of plants were subjected to antimicrobial assay through agar well and agar tube dilution method. Extracts were tested against three gram positive bacteria strain i.e. Staphylococcus aureus, Staphylococcus epidermidis, Kelebsiella pneumonia and two gram negative bacteria strain i.e. Pseudomonas spp and Escherichia coli whereas antifungal activity was evaluated against Fusarium sp. and Alternaria sp.

Results: Tested species show concentration dependent antibacterial activity with 4.67% – 83.05% inhibition against all tested bacterial strains. However gram negative bacterial strains are found to be most resistant. Among plant extracts B. biternata and M. Africana show highest antibacterial activity with percentage inhibition ranged between 83.05% -14.4%. Against fungal strains, three plants i.e B. biternata, C.tuberculate, C. serrata were tested, and inhibition ranged between 34% -61% was obtained.

Conclusions: B.biternata, and M. Africana are appeared to have high antibacterial properties, if further analysed can served as pre-requisite for the discovery of potent drugs.