Aim: Antimicrobial resistance presents a growing concern worldwide. Medical students are potential antimicrobial prescribers and stewards following graduation as doctors. The aim of this study was to assess the knowledge regarding antimicrobial resistance (AMR) and antibiotic use among pre-final year and final year medical school students of Ebonyi State University, Nigeria.
Materials and Methods: A cross sectional study was conducted among all the 184 pre-final year and final year medical students of the College of Medicine in Ebonyi State University, Nigeria. Information was collected using a semi-structured, self-administered questionnaire and data analysed with Epi-Info Version 7.2. Analytical decisions were considered significant at P < 0.05.

Results: Respondents were mostly males (62.5%), aged 20-29 years (68.9%) with 60.9% of them in final year. Eight in 10 of them had used antibiotics in the past year and desired more education on antimicrobial resistance and use. Majority 119 (64.7%) respondents had good knowledge of antimicrobial resistance and use however 39% answered that bacteria cause common cold. Only 103 (56.0%) of them had positive practice of antibiotic use. Only 8.2% of respondents always consulted a doctor before starting an antibiotic and 37.2% of them never discarded their remaining leftover medications. Knowledge was associated with respondent’s gender (P=0.035) while practice was associated with class of study (P<0.001).
Conclusion: There was good knowledge of antimicrobial resistance and use however practice levels were poor. There is need to enrich existing courses and training about antimicrobial use in the curriculum of the medical schools with more emphasis on antimicrobial stewardship.